What's New Scooby Doo picks up where the original Scooby Doo tv show left off. It features Shaggy, Scooby, Daphne, Velma, and Fred pretty much the same age and as they were in the original television show. This was a welcome departure from the Pup Named Scooby Doo series, where the gang was featured in their childhood. This series also has guest stars, but unlike mid 1970's episodes with the Harlem Globetrotters, the Three Stooges, Don Knotts, Sonny & Cher and Batman & Robin, and others, What's New Scooby Doo episodes are a lot less campy and a lot more entertaining.
The series also introduces and re-introduces characters that appear throughout the series and movies. Luna, Thorn, and Dusk, the Hex Girls, appear in two movies Scooby Doo and the Witch's Ghost, Legend of the Vampire. But they also appear in the Vampire Strikes Back and episode from this series. Other recurring characters are Melborne O'Reilly a rugged, man's man that Fred looks up to and J.J. Hakimoto, film producer.